Dedicated to the
Health and Welfare of All Cats
Font Size

Cat Health News Blog

A resource for dedicated cat supporters

Since its start in 2007, Cat Health News has featured the latest information on feline health. The bi-weekly blog is a mix of the most current published research from Winn-funded research and other sources. There are over 570 blog items and more than 1,000 subscribers through the RSS feed.

icon-blogWinn-funded research is specifically noted by the small green cat.

  • Feline calicivirus isolated from a tiger

    Oct 21, 2016
    Tiana, J, Liu D, et al. Molecular characterization of a feline calicivirus isolated from tiger and its pathogenesis in cats. Vet Microbiol. 2016 Aug 30;192:110-7.   

    Feline calicivirus causes respiratory disease in cats and is one of the most common pathogens affecting cats.

    Recently, a strain of calicivirus was isolated from the feces of a healthy Siberian Tigersiberian_tiger_513922 housed in a zoo in China. Genetic analysis revealed that this virus is distinct from other Chinese isolates, and similar to one from the USA. The Chinese isolate also grew faster in the laboratory than other strains. When given to domestic cats, it was of a virulent phenotype, proving to be highly contagious and lethal. The investigators found that this tiger isolate caused severe lung damage, and also led to intestinal damage.  

    This is the first report of molecular characterization of a feline calicivirus from tigers. It is not clear if this virus is capable of causing disease in tigers, but in domestic cats it is highly lethal. This may be an example of host adaptation to a virus strain and vice versa, where in the natural host, little disease is seen. (MK)

    See also:
    Rong S, Lowery D, et al. Characterization of an avirulent FCV strain with a broad serum cross-neutralization profile and protection against challenge of a highly virulent vs feline calicivirus. Virus Res.2014 Aug 8;188:60-7.

    Siberian tiger feline calicivirus respiratory disease

    More on cat health:

    Winn Feline Foundation Library
    Find us on Facebook
    Follow us on Twitter
    Pin with us on Pinterest
    Join us on Google+