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Cat Health News Blog

A resource for dedicated cat supporters

Since its start in 2007, Cat Health News has featured the latest information on feline health. The bi-weekly blog is a mix of the most current published research from Winn-funded research and other sources. There are over 570 blog items and more than 1,000 subscribers through the RSS feed.


icon-blogWinn-funded research is specifically noted by the small green cat.

  • New approach to feline cancer therapy

    Jan 30, 2012

    Final report, Winn grant 09-031
    Investigation of myxoma virus as an oncolytic agent in feline cancer cell cultures
    Investigator: Amy L. MacNeill
    College of Veterinary Medicine, University of Illinois

    A current area of research focuses on novel cancer therapeutics that may minimize deleterious effects and reduce failure compared with existing cancer treatments. One approach under investigation is oncolytic virotherapy – the use of viruses that infect and destroy cancer cells but not normal cells. Oncolytic virotherapy may improve the efficacy of chemotherapy or radiation therapy for some types of cancers. There is evidence that a host-restricted poxvirus, myxoma virus (a rabbit-specific virus), can be used as a safe, effective cancer treatment based on studies in mice. To date, there are no published studies that determine whether myxoma virus can infect feline cancer cells. The authors have shown in this study that myxoma virus can induce oncolysis in two primary feline carcinoma cell cultures. Cell death occurred in primary feline cancer cells within 48 hours of inoculation with myxoma virus. The results indicate that further studies using myxoma virus as an oncolytic treatment for feline cancers is warranted. [VT]

    cancer

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